Author

Hong-Jin Shu

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

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Assay:electronic health records· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Charles F. ZorumskiiD· 2 shared Steven J. MennerickiD· 2 shared Ajeet KumariD· 1 shared Ann M. Benz· 1 shared Brenda C. ShieldsiD· 1 shared Douglas F. CoveyiD· 1 shared Jiyong HongiD· 1 shared Mariangela ChisariiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Charles F. ZorumskiORCID

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2 papers

Recent·Most cited

Subunit selective modulation of GABAA receptors using pharmacogenetically tethered neurosteroids

Ajeet Kumar, Hong-Jin Shu, Mariangela Chisari, Mingxing Qian, Yuanjian Xu, Pyeonghwa Jeong, Brenda C. Shields, Jiyong Hong, Michael R. Tadross, Douglas F. Covey, Charles F. Zorumski, Steven J. Mennerick

The paper develops a DART platform to selectively modulate GABAA receptor subunits using neurosteroids, identifying C11-linked compounds that enhance GABA currents in 4/{delta}-containing receptors.

bioRxiv · Apr 8, 2026 · PreprintNeuroscience

δ-containing GABAA receptors on parvalbumin interneurons modulate neuronal excitability and network dynamics in the mouse medial prefrontal cortex

Xinguo Lu, Hong-Jin Shu, Peter M. Lambert, Ann M. Benz, Charles F. Zorumski, Steven J. Mennerick

This study shows that δ-containing GABAA receptors in PV interneurons regulate their excitability and inhibit pyramidal neurons in the mPFC, affecting network dynamics.

bioRxiv · Jun 14, 2024 · PreprintNeuroscience