Author

Mingkun Wu

University of TorontoORCID 0000-0002-0366-3892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

Benjamin J. BlencoweiD· 2 shared Anne‐Claude GingrasiD· 1 shared Archa H. FoxiD· 1 shared B. Raktan Ahmed· 1 shared Boris J.A. DyakoviD· 1 shared Caroline ThiviergeiD· 1 shared Edyta Marcon· 1 shared Giovanni L. BurkeiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Benjamin J. BlencoweORCID

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2 papers

Recent·Most cited

Recruitment of the m6A/Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

Syed Nabeel‐Shah, Shuye Pu, Giovanni L. Burke, Nujhat Ahmed, Ulrich Braunschweig, Shaghayegh Farhangmehr, Hyunmin Lee, Mingkun Wu, Zuyao Ni, Hua Tang, Guoqing Zhong, Edyta Marcon, Zhaolei Zhang, Benjamin J. Blencowe, Jack F. Greenblatt

This study identifies ZBTB48 as a regulator of FTO's substrate selectivity by facilitating its binding to m6A/m6Am-containing RNAs, affecting RNA decay and cancer cell growth.

Genome biology · Sep 19, 2024Peer-reviewedMolecular Biology

Spatial proteomic mapping of human nuclear bodies reveals new functional insights into RNA regulation

Boris J.A. Dyakov, Simon Kobelke, B. Raktan Ahmed, Mingkun Wu, Jonathan F. Roth, Vesal Kasmaeifar, Zhen‐Yuan Lin, Ji‐Young Youn, Caroline Thivierge, Kieran R. Campbell, Thomas F. Duchaîne, Benjamin J. Blencowe, Archa H. Fox, Anne‐Claude Gingras

The paper maps human nuclear bodies using proximity proteomics, identifying new components and regulatory functions in RNA regulation.

bioRxiv · Jul 3, 2024 · PreprintCell Biology