Author

I. A. Blair

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

N. W. Snyder· 2 shared A. Angajala· 1 shared A. Bostwick· 1 shared A. D. Arroyo· 1 shared A. J. Worth· 1 shared B. E. Schaffer· 1 shared B. Singh· 1 shared C. A. Mesaros· 1 shared

Activity by Year

2016-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

N. W. Snyder

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Author profile →

3 papers

Recent·Most cited

Primary saturation of α,β-unsaturated carbonyl containing fatty acids does not abolish electrophilicity

N. W. Snyder, J. O'Brien, B. Singh, G. Buchan, A. D. Arroyo, X. Liu, A. Bostwick, E. L. Varner, A. Angajala, R. W. Sobol, I. A. Blair, C. A. Mesaros, S. G. Wendell

This study investigates the electrophilicity of saturated oxo-fatty acids and finds that mono-saturation retains electrophilicity, while double saturation abolishes it, implicating PTGR1 in their metabolism.

bioRxiv · Sep 24, 2020Biochemistry

Glutamine deprivation triggers NAGK-dependent hexosamine salvage

S. L. Campbell, C. Mesaros, L. Izzo, H. Affronti, T. Tsang, M. Noji, B. E. Schaffer, K. Sun, S. Trefely, S. Kruijning, J. Blenis, I. A. Blair, K. E. Wellen

This study shows that glutamine deprivation in pancreatic ductal adenocarcinoma cells increases free GlcNAc and activates NAGK-dependent hexosamine salvage to support tumor growth.

bioRxiv · Sep 13, 2020Cancer Biology

Bioorthogonal pro-metabolites for profiling short chain fatty acylation

W. R. Sinclair, T. T. Zengeya, J. M. Garlick, A. J. Worth, I. A. Blair, N. W. Snyder, J. L. Meier

This paper introduces bioorthogonal pro-metabolites to profile short chain fatty acylation in cells, identifying novel protein targets and characterizing their metabolic and enzymatic effects.

bioRxiv · Dec 30, 2016Cell Biology