I. H. Heijink

E-cigarette vapour induces cellular senescence in primary lung fibroblasts and may contribute to lung pathology

This study shows E-cigarette vapour induces cellular senescence in primary human lung fibroblasts, impairing tissue repair, but not in a mouse model.

Three dimensional fibrotic extracellular matrix directs microenvironment fiber remodeling by fibroblasts

This study shows that 3D fibrotic ECM hydrogels alter fibroblast fiber organization and mechanical properties, promoting pro-fibrotic responses.