Author

S. Tzipori

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Organism:E. coli· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

C. B. Shoemaker· 2 shared J. Jaskiewicz· 2 shared J. M. Tremblay· 2 shared A. Antia· 1 shared A. Dehkharghani· 1 shared A. Manjula-Basavanna· 1 shared A. Sadeqi· 1 shared A. Sheoran· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

C. B. Shoemaker

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Author profile →

4 papers

Recent·Most cited

Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus.

V. Greigert, I. Saraav, J. Son, D. Dayao, A. Antia, S. Tzipori, W. Witola, T. S. Stappenbeck, S. Ding, L. D. Sibley

This study develops a human air-liquid interface culture system for Cryptosporidium hominis, revealing it induces type III interferon and reduces Rotavirus infectivity.

bioRxiv · Aug 30, 2023 · PreprintMicrobiology

Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies

M. Debatis, H. Danz, J. M. Tremblay, K. Gaspie, R. Kudej, V. Vigdorovich, N. Sather, J. Jaskiewicz, S. Tzipori, C. B. Shoemaker

This study compares the functional and structural stability of monomeric and multimeric camelid VHHs in vitro and in vivo, showing some VHHs can match the stability of conventional antibodies in the gut.

bioRxiv · May 15, 2023Bioengineering

Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917

I. Gelfat, Y. Aqeel, J. M. Tremblay, J. Jaskiewicz, A. Shrestha, J. N. Lee, S. Hu, X. Qian, L. Magoun, A. Sheoran, D. Bedenice, C. Giem, A. Manjula-Basavanna, M. S. Osbourne, S. Tzipori, , N. S. Joshi

The paper develops VHH-based therapeutics displayed on probiotic E. coli Nissle 1917 to target enteric pathogens, showing they can bind and neutralize virulence factors.

bioRxiv · Jun 18, 2021Microbiology

Ingestible Osmotic Pill for In-vivo Sampling of Gut Microbiome

H. Rezaei Nejad, B. C. M. Oliveira, A. Sadeqi, A. Dehkharghani, I. Kondova, J. A. M. Langermans, J. S. Guasto, S. Tzipori, G. Widmer, S. R. Sonkusale

This paper introduces an ingestible osmotic pill for in vivo gut microbiome sampling and shows it accurately captures bacterial populations from different gut regions.

bioRxiv · Jul 3, 2019 · PreprintBioengineering