Author

I. Vakonakis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

A. L. Kantsadi· 2 shared A. Menzel· 1 shared A. Passecker· 1 shared C. A. Lutomski· 1 shared C. J. Schofield· 1 shared C. Padeste· 1 shared C. V. Robinson· 1 shared E. Cattermole· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiophysics

A. L. Kantsadi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Phase separation of a microtubule plus-end tracking protein into a fluid fractal network

M. P. Czub, F. Uliana, T. Grubic, C. Padeste, K. A. Rosowski, E. R. Dufresne, A. Menzel, I. Vakonakis, U. Gasser, M. O. Steinmetz

This study investigates the phase separation of Bik1, a +TIP protein, revealing its conformational changes and fractal structure in liquid condensates.

bioRxiv · Apr 19, 2024Biochemistry

The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

E. Hitz, N. Wiedemar, A. Passecker, N. M. B. Brancucci, I. Vakonakis, P. Maeser, T. S. Voss

This study identifies PfPDK1 as an essential upstream activator of PfPKAc in malaria parasites, crucial for parasite survival and a potential drug target.

bioRxiv · May 27, 2021Microbiology

Allosteric inhibition of the SARS-CoV-2 main protease - insights from mass spectrometry-based assays

T. J. El-Baba, C. A. Lutomski, A. L. Kantsadi, T. R. Malla, T. John, V. Mikhailov, J. R. Bolla, C. J. Schofield, N. Zitzmann, I. Vakonakis, C. V. Robinson

The paper uses mass spectrometry to study SARS-CoV-2 main protease dimerization and allosteric inhibition by small molecules.

bioRxiv · Jul 29, 2020Biophysics

A COVID Moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy.

A. L. Kantsadi, E. Cattermole, M.-T. Matsoukas, G. A. Spyroulias, I. Vakonakis

The paper assesses ligand binding to SARS-CoV-2 main protease using STD-NMR spectroscopy and shares data to aid drug design.

bioRxiv · Jun 17, 2020Biochemistry