Author

Ian J. White

MRC Laboratory for Molecular Cell Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron CrowtheriD· 1 shared Alessandro Bossio· 1 shared Alison C. LloydiD· 1 shared Amanda M. PocratskyiD· 1 shared Benjamin J. O’CallaghaniD· 1 shared Calvin Chad SmithiD· 1 shared Davor IvankoviciD· 1 shared Filipe NascimentoiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperMicrobiology

Aaron CrowtherORCID

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Author profile →

5 papers

Recent·Most cited

PKA can adopt structural or enzymatic roles depending on its anchoring site

Timothy W. Church, Yuelin Luo, Ryan S. Dowsell, Ian J. White, Matthew G. Gold

This study shows that PKA can act as either an enzymatic or structural component depending on its anchoring site, using a SpyCatcher-SpyTag strategy to compare AKAP functions.

bioRxiv · Aug 15, 2026 · PreprintMolecular Biology

Gut-relevant short-chain fatty acids modulate host-pathogen dynamics of uropathogenic Escherichia coli at the colonic epithelial interface

Nicholas Yuen, Ramón Garcia Maset, Wendy Wang, Manas Kubal, Zekun Chen, V. H. Chu, Ian J. White, Jinhui Gao, Francesca Torelli, Aaron Crowther, Laia Pasquina-Lemonche, Jennifer L. Rohn

This study investigates how gut-derived short-chain fatty acids affect uropathogenic Escherichia coli behavior and host-pathogen interactions at the colonic epithelial interface.

bioRxiv · Jan 19, 2026 · PreprintMicrobiology

Pathophysiology of Dyt1 dystonia is mediated by spinal cord dysfunction

Amanda M. Pocratsky, Filipe Nascimento, Mustafa Görkem Özyurt, Ian J. White, Roisin Sullivan, Benjamin J. O’Callaghan, Calvin Chad Smith, Sunaina Surana, Marco Beato, Robert M. Brownstone

This study shows that spinal cord dysfunction contributes to DYT1 dystonia by creating mouse models with dystonia-like symptoms.

bioRxiv · May 5, 2022 · PreprintNeuroscience

AP-4 mediated ATG9A sorting underlies axonal and autophagosome biogenesis defects in a mouse model of AP-4 deficiency syndrome

Davor Ivankovic, James Drew, Flavie Lesept, Ian J. White, Guillermo López‐Doménech, Sharon A. Tooze, Josef T. Kittler

This study shows that AP-4 deficiency in mice causes axonal and autophagosome biogenesis defects by impairing ATG9A sorting from the trans-Golgi network.

Autophagy · May 29, 2019Peer-reviewedNeuroscience

Macrophages enforce the blood nerve barrier

Liza Malong, Ilaria Napoli, Ian J. White, Salome Stierli, Alessandro Bossio, Alison C. Lloyd

This study identifies macrophages as key components of the blood-nerve barrier (BNB) that reinforce the barrier by engulfing leaked material, contrasting with the blood-brain barrier (BBB) which relies more on endothelial cells.

bioRxiv · Jan 3, 2019 · PreprintNeuroscience