Author

A. Dvorkin-Gheva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1

Frequent Co-Authors

K. Ask· 2 shared A. Ayoub· 1 shared A. Banerjee· 1 shared A. C. Doxey· 1 shared A. Chandiramohan· 1 shared A. John· 1 shared A. Naqvi· 1 shared B. G. Wouters· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersPathology

K. Ask

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Author profile →

3 papers

Recent·Most cited

FK506-binding protein 13 expression is upregulated in interstitial lung disease and correlated with clinical severity: a potentially protective role.

V. Tat, E. A. Ayaub, A. Ayoub, M. Vierhout, S. Naiel, M. Padwal, S. Abed, O. Mekhael, K. Tandon, S. D. Revill, T. Yousof, P.-S. Bellaye, P. Kolb, A. Dvorkin-Gheva, A. Naqvi, , K. Ask

This study shows FKBP13 is upregulated in interstitial lung diseases and correlates with disease severity, suggesting a protective role against fibrosis.

American Journal of Respiratory Cell and Molecular Biology · Feb 1, 2021Peer-reviewedPathology

NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

P. Jain, A. Dvorkin-Gheva, E. Mollen, M. Xie, F. Jessa, P. Dhavarasa, S. Chung, K. R. Brown, G. H. Jang, F. Notta, J. Moffat, D. Hedley, P. C. Boutros, B. G. Wouters, M. Koritzinsky

This study identifies NOX4 as a link between metabolic deregulation and ER-specific redox vulnerability in PDAC, suggesting PRDX4 as a therapeutic target for pancreatic cancer.

bioRxiv · Oct 8, 2020Cancer Biology

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

J. A. Aguiar, B. J.-M. Tremblay, M. J. Mansfield, O. Woody, B. Lobb, A. Banerjee, A. Chandiramohan, N. Tiessen, A. Dvorkin-Gheva, S. Revill, M. S. Miller, C. Carlsten, L. Organ, C. Joseph, A. John, , J. A. Hirota

The paper examines gene expression and protein localization of potential SARS-CoV-2 receptors in human airway epithelial cells and lung tissue, finding low ACE2 expression and confirming other candidate receptors.

bioRxiv · Apr 7, 2020Immunology