Author

J. Bellamy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 5

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Organism:human· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1

Frequent Co-Authors

K. Malik· 4 shared M. Kollareddy· 4 shared M. Szemes· 4 shared D. Catchpoole· 3 shared Z. Melegh· 3 shared A. Greenhough· 2 shared E. E. Vincent· 2 shared J. H. Park· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersCancer Biology

K. Malik

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5 papers

Recent·Most cited

Glutamine addiction is targetable via altering splicing of nutrient sensors and epitranscriptome regulators

J. Bojko, M. Kollareddy, M. Szemes, J. Bellamy, E. Poon, A. Moukachar, D. Legge, E. E. Vincent, N. Jones, S. Malik, A. Greenhough, A. Paterson, J. H. Park, K. Gallacher, L. Chesler, K. Malik

This study shows PRMT5 inhibition targets MNA neuroblastoma by altering splicing of nutrient sensors and epitranscriptome regulators, leading to growth inhibition and apoptosis.

bioRxiv · Feb 28, 2024 · PreprintCancer Biology

Identifying targetable metabolic dependencies across colorectal cancer progression

D. N. Legge, E. Stanko, A. K. Holt, C. J. Bull, T. J. Collard, M. Kollareddy, J. Bellamy, S. Groves, E. H. Ma, E. Hazelwood, D. Qualtrough, B. Amulic, K. N. Malik, A. C. Williams, N. Jones, E. E. Vincent

This study identifies asparagine synthesis as a metabolic vulnerability in late-stage colorectal cancer cells, showing that blocking asparagine synthetase inhibits their proliferation.

bioRxiv · Mar 23, 2022Cancer Biology

Transcriptomic analyses of MYCN-regulated genes in anaplastic Wilms' tumour cell lines reveals oncogenic pathways and potential therapeutic vulnerabilities

M. Szemes, Z. Melegh, J. Bellamy, J. H. Park, B. Chen, A. Greenhough, D. Catchpoole, K. Malik

bioRxiv · Jan 11, 2021Cancer Biology

A Wnt-BMP4 signalling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma

M. Szemes, Z. Melegh, J. Bellamy, M. Kollareddy, D. Catchpoole, K. Malik

This study shows that Wnt-BMP4 signaling induces MSX and NOTCH proteins, leading to growth suppression and differentiation in neuroblastoma.

bioRxiv · Feb 7, 2020Cancer Biology

Increased efficacy of histone methyltransferase G9a inhibitors against MYCN-amplified Neuroblastoma

J. Bellamy, K. Malik, M. Szemes, Z. Melegh, A. Dallosso, M. Kollareddy, D. Catchpoole

This study shows G9a inhibitors are more effective against MYCN-amplified neuroblastoma, with G9a depletion triggering apoptosis specifically in these cells.

bioRxiv · Nov 22, 2019Cancer Biology