Author

J. Carnevale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:CRISPR screen· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Ashworth· 3 shared A. Marson· 3 shared E. Shifrut· 3 shared A. M. Weeks· 1 shared A. Satpathy· 1 shared A. Valencia· 1 shared C. Bui· 1 shared C. Duffy· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

A. Ashworth

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

J. Belk, W. Yao, N. Ly, K. Freitas, Y.-T. Chen, Q. Shi, A. Valencia, E. Shifrut, N. Kale, K. Yost, C. Duffy, M. Hwee, Z. Miao, A. Ashworth, C. Mackall, , A. Satpathy

This study identifies chromatin remodeling factors that limit T cell persistence using CRISPR screens and shows their impact on anti-tumor immunity.

bioRxiv · Apr 20, 2022Immunology

Hypoxia is a dominant remodeler of the CD8+ T cell surface proteome relative to activation and regulatory T cell-mediated suppression

J. R. Byrnes, A. M. Weeks, J. Carnevale, E. Shifrut, L. Kirkemo, A. Ashworth, A. Marson, J. A. Wells

This study compares how hypoxia and regulatory T cells affect the CD8+ T cell surface proteome, finding hypoxia has a more significant impact than Treg-mediated suppression.

bioRxiv · Jun 7, 2021Immunology

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

E. Shifrut, J. Carnevale, V. Tobin, T. L. Roth, J. M. Woo, C. Bui, P. J. Li, M. Diolaiti, A. Ashworth, A. Marson

This study uses CRISPR screens in primary human T cells to identify regulators of immune function and cancer cell killing.

bioRxiv · Aug 3, 2018Immunology