Author

J. G. Cyster

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. H. Settle· 1 shared A. M. Yakimov· 1 shared A. Sawh· 1 shared A.-L. L. Sepp· 1 shared B. J. Laidlaw· 1 shared B. Y. Winer· 1 shared C. Jeronimo· 1 shared F. Geissmann· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

A. H. Settle

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells

B. Y. Winer, A. H. Settle, A. M. Yakimov, C. Jeronimo, T. Lazarovt, M. Tipping, M. Saoi, A. Sawh, A.-L. L. Sepp, M. Galiano, J. S. A. Perry, Y. Y. Wong, F. Geissmann, J. Cross, T. Zhou, , M. Huse

This study shows that plasma membrane abundance regulates phagocytic capacity and post-phagocytic migration in myeloid cells, with G{beta}4 deficiency leading to increased phagocytosis and altered trafficking.

bioRxiv · Sep 12, 2023 · PreprintCell Biology

Transmembrane protein CD69 acts as an S1PR1 agonist

H. Chen, Y. Qin, M. Chou, J. G. Cyster, X. Li

This study reveals that CD69 acts as a transmembrane protein agonist of S1PR1, promoting Gi-dependent internalization and inhibiting lymphocyte egress.

bioRxiv · Feb 13, 2023Biophysics

The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development

B. J. Laidlaw, L. Duan, Y. Xu, S. E. Vazquez, J. G. Cyster

The paper identifies Hhex and Tle3 as regulators of memory B cell differentiation through single-cell RNA-seq and CRISPR screening, showing their interaction and functional roles.

bioRxiv · Feb 25, 2020Immunology