Author

M. Saoi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Bhattacharjee· 1 shared A. H. Settle· 1 shared A. J. Chui· 1 shared A. M. Yakimov· 1 shared A. R. Griswold· 1 shared A. Sawh· 1 shared A.-L. L. Sepp· 1 shared B. Y. Winer· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Bhattacharjee

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells

B. Y. Winer, A. H. Settle, A. M. Yakimov, C. Jeronimo, T. Lazarovt, M. Tipping, M. Saoi, A. Sawh, A.-L. L. Sepp, M. Galiano, J. S. A. Perry, Y. Y. Wong, F. Geissmann, J. Cross, T. Zhou, , M. Huse

This study shows that plasma membrane abundance regulates phagocytic capacity and post-phagocytic migration in myeloid cells, with G{beta}4 deficiency leading to increased phagocytosis and altered trafficking.

bioRxiv · Sep 12, 2023 · PreprintCell Biology

Cytosolic peptide accumulation activates the NLRP1 and CARD8 inflammasomes

E. L. Orth-He, H.-C. Huang, S. D. Rao, Q. Wang, Q. Chen, C. M. O'Mara, A. J. Chui, M. Saoi, A. R. Griswold, A. Bhattacharjee, D. P. Ball, J. R. Cross, D. A. Bachovchin

This study identifies cytosolic peptide accumulation as a danger signal that activates NLRP1 and CARD8 inflammasomes by promoting NT degradation and disrupting DPP9-mediated sequestration of CT fragments.

bioRxiv · Mar 22, 2022 · PreprintImmunology