Author

J. J. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Animal Behavior & Cognition· 1 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:behavioral assay· 1

Frequent Co-Authors

A. N. Hata· 3 shared K. Dionne· 2 shared A. Abbasi· 1 shared A. Acker· 1 shared A. Do· 1 shared A. J. O. Dede· 1 shared A. L. Fairhall· 1 shared A. Langenbucher· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A. N. Hata

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Dynamics of endogenous and water cortisol release in Asian Seabass Lates calcarifer after acute stress in a farm scale recirculating aquaculture system

M. R. Tan, K. M. M. Aung, N. A. b. M. Salleh, J. Y. A. Tan, K. X. Chua, G. J. Doblado, K. L. Chua, V. Tham, J. J. Lin, V. Chaganty, D. M. Yusoff, S. Vij, X. Su, L. Sutarlie, C. L. Wee

This study measures cortisol dynamics in Asian Seabass under acute stress in a farm-scale RAS, showing varying temporal patterns in plasma, mucus, fin, and water cortisol.

bioRxiv · Sep 20, 2023 · PreprintPhysiology

Comparing rapid rule-learning strategies in humans and monkeys

V. Goudar, J.-W. Kim, Y. Liu, A. J. O. Dede, M. J. Jutras, I. Skelin, M. Ruvalcaba, W. Chang, A. L. Fairhall, J. J. Lin, R. T. Knight, E. A. Buffalo, X.-J. Wang

This study compares rule-learning strategies between humans and macaque monkeys in a card-sorting task, finding differences in speed and error patterns.

bioRxiv · Jan 10, 2023 · PreprintAnimal Behavior & Cognition

LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers

C. Li, M. U. Syed, A. Nimbalkar, Y. Shen, C. Fraser, Z. Inde, X. Qin, J. Ouyang, J. Kreuzer, S. E. Clark, G. E. Kelley, E. Hensley, A. Oh, M. Walcott, R. Morris, , A. N. Hata

This study shows LKB1 suppresses JNK-dependent stress signaling in KRAS-mutant lung cancers, revealing a therapy-induced vulnerability that could improve KRAS-targeted therapies.

bioRxiv · Sep 29, 2022 · PreprintCancer Biology

Structural and functional analysis of lorlatinib analogs reveals roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer

A. Shiba-Ishii, T. W. Johnson, I. Dagogo-Jack, M. Mino-Kenudson, T. R. Johnson, P. Wei, S. L. Weinrich, M. A. McTigue, M. A. Walcott, L. Nguyen-Phuong, K. Dionne, A. Acker, L. Kiedrowski, A. Do, J. L. Peterson, , A. N. Hata

This study identifies lorlatinib-resistant ALK mutations and evaluates analogs to develop targeted therapies for compound resistance in ALK-positive lung cancer.

Nature Cancer · Jun 20, 2022Peer-reviewedCancer Biology

Discrete LAT condensates encode antigen information from single pMHC:TCR binding events

D. B. McAffee, M. K. O'Dair, J. J. Lin, S. T. Low-Nam, K. B. Wilhelm, S. Kim, S. Morita, J. T. Groves

The paper shows that LAT condensates form in response to pMHC:TCR binding events, with condensation probability linked to binding dwell time and a mutation affecting this process.

bioRxiv · Dec 16, 2021Biophysics

APOBEC3A drives acquired resistance to targeted therapies in non-small cell lung cancer

H. Isozaki, A. Abbasi, N. Nikpour, A. Langenbucher, W. Su, M. Stanzione, H. Frisco-Cabanos, F. M. Siddiqui, N. Phan, P. Jalili, S. Oh, D. Timonina, S. Bilton, M. Gomez-Caraballo, H. L. Archibald, , A. N. Hata

This study shows that APOBEC3A mutagenesis driven by targeted therapies promotes drug resistance in non-small cell lung cancer.

bioRxiv · Jan 20, 2021Cancer Biology