Author

J. J. Tu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

S. R. Permar· 3 shared M. Dennis· 2 shared R. Goswami· 2 shared A. Chahroudi· 1 shared A. D. Curtis· 1 shared A. Kumar· 1 shared A. N. Nelson· 1 shared A. S. Miller· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

S. R. Permar

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Author profile →

3 papers

Recent·Most cited

Zika virus-specific IgM elicited during pregnancy exhibits ultrapotent neutralization

T. Singh, K.-K. Hwang, A. S. Miller, R. L. Jones, C. A. Lopez, C. Giuberti, M. A. Gladden, I. Miller, H. S. Webster, J. A. Eudailey, K. Luo, T. Von Holle, R. J. Edwards, S. Valencia, K. E. Burgomaster, , M. Bonsignori

This study identifies a potent ZIKV-neutralizing IgM antibody from a pregnant woman and shows its protective efficacy in mice.

bioRxiv · Nov 23, 2021Immunology

Oral Hsp90 inhibitor, SNX-5422, attenuates SARS-CoV-2 replication and dampens inflammation in airway cells.

R. Goswami, V. S. Russell, J. J. Tu, P. Hughes, F. Kelly, S. N. Langel, J. Steppe, S. M. Palmer, T. Haystead, M. Blasi, S. R. Permar

This study shows that the Hsp90 inhibitor SNX-5422 reduces SARS-CoV-2 replication and inflammation in airway cells, suggesting its potential as an early therapeutic.

bioRxiv · Feb 23, 2021Microbiology

Analytical treatment interruption after short-term anti-retroviral therapy in a postnatally SHIV infected infant rhesus macaque model

R. Goswami, A. N. Nelson, J. J. Tu, M. Dennis, L. Feng, A. Kumar, J. Mangold, R. J. Mangan, C. Mattingly, A. D. Curtis, V. Obregon-Perko, M. Mavigner, J. Pollara, G. M. Shaw, K. J. Bar, , S. R. Permar

This paper develops an infant rhesus macaque model of SHIV infection and analytical treatment interruption to study viral rebound and identify biomarkers for pediatric HIV functional cure strategies.

bioRxiv · Jun 11, 2019Immunology