Vaccine-induced, high magnitude HIV Env-specific antibodies with Fc-mediated effector functions are insufficient to protect infant rhesus macaques against oral SHIV infection
A. D. Curtis, P. T. Saha, M. Dennis, S. J. Berendam, S. M. Alam, G. Ferrari, P. A. Kozlowski, G. G. Fouda, M. G. Hudgens, K. K. A. Van Rompay, J. Pollara, S. R. Permar, K. De Paris
This study tests a vaccine regimen in infant rhesus macaques, finding that Env-specific antibodies with Fc effector functions do not prevent oral SHIV infection.
bioRxiv · Oct 11, 2021Immunology