Author

T. Von Holle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:non-human primate· 1

Frequent Co-Authors

M. A. Moody· 2 shared R. J. Edwards· 2 shared S. M. Alam· 2 shared A. Foulger· 1 shared A. N. Macintyre· 1 shared A. S. Miller· 1 shared A. Sanzone· 1 shared A. Schafer· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

M. A. Moody

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Author profile →

3 papers

Recent·Most cited

Infant antibody repertoires during the first two years of influenza vaccination

M. Kuraoka, N. C. Curtis, A. Watanabe, H. Tanno, S. Shin, K. Ye, E. Macdonald, O. Lavidor, S. Kong, T. Von Holle, I. W. Windsor, G. C. Ippolito, G. Georgiou, E. B. Walter, G. H. Kelsoe, , J. Lee

This paper studies how influenza vaccination in infants shapes their antibody responses, finding that vaccination can lead to immune imprinting similar to infection, with shifts in B-cell specificity and adult-like antibody repertoires after the second year.

bioRxiv · Sep 13, 2022Immunology

Zika virus-specific IgM elicited during pregnancy exhibits ultrapotent neutralization

T. Singh, K.-K. Hwang, A. S. Miller, R. L. Jones, C. A. Lopez, C. Giuberti, M. A. Gladden, I. Miller, H. S. Webster, J. A. Eudailey, K. Luo, T. Von Holle, R. J. Edwards, S. Valencia, K. E. Burgomaster, , M. Bonsignori

This study identifies a potent ZIKV-neutralizing IgM antibody from a pregnant woman and shows its protective efficacy in mice.

bioRxiv · Nov 23, 2021Immunology

The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

D. Li, R. J. Edwards, K. Manne, D. R. Martinez, A. Schafer, S. M. Alam, K. Wiehe, X. Lu, R. Parks, L. L. Sutherland, T. H. Oguin, C. McDanal, L. G. Perez, K. Mansouri, S. M. C. Gobeil, , Petzol

This study examines SARS-CoV-2 neutralizing and infection-enhancing antibodies, showing in vitro enhancement does not always lead to in vivo disease enhancement, but can cause increased lung inflammation in monkeys.

bioRxiv · Dec 31, 2020 · PreprintImmunology