Author

J. Kaivola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. Ivaska· 2 shared J. R. W. Conway· 2 shared A. K. Najumudeen· 1 shared A. Padzik· 1 shared A. S. A. Poulsen· 1 shared D. Abankwa· 1 shared E. Peuhu· 1 shared E. Wang· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

J. Ivaska

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Author profile →

2 papers

Recent·Most cited

Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

J. Lilja, J. Kaivola, J. R. W. Conway, J. Vuorio, H. Parkkola, P. Roivas, T. Varila, G. Jacquemet, E. Peuhu, E. Wang, U. Pentikäinen, I. M. D. Posada, H. Hamidi, A. K. Najumudeen, O. J. Sansom, , J. Ivaska

This study identifies SHANK3 as a RAS interactor that limits oncogenic KRAS signaling, and shows that disrupting its interaction with KRAS induces cell death in KRAS-mutant cancers.

bioRxiv · Sep 21, 2022 · PreprintCancer Biology

A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance

H. Al-Akhrass, J. R. W. Conway, A. S. A. Poulsen, I. Paatero, J. Kaivola, A. Padzik, O. M. Andersen, J. Ivaska

This study identifies a feed-forward loop involving SorLA and HER3 that enhances heregulin response and neratinib resistance in breast cancer.

bioRxiv · Jun 10, 2020Cancer Biology