Author

j. L. Witztum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. F. M. Pinto· 1 shared A. Hammond· 1 shared A. Quach· 1 shared A. R. Pessentheiner· 1 shared A. W. T. Chiang· 1 shared A. Williams· 1 shared B. Emu· 1 shared B. McDonald· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. F. M. Pinto

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2 papers

Recent·Most cited

The Human Milk Oligosaccharide 3-Sialyllactose Promotes Inflammation Resolution and Reduces Atherosclerosis Development in Mice.

A. R. Pessentheiner, N. J. Spann, C. A. Autran, B. Ramms, A. W. T. Chiang, K. V. Grunddal, Y. Wang, A. Quach, L. M. Booshehri, A. Hammond, C. Tognaccini, J. Latasiewicz, j. L. Witztum, H. M. Hoffman, N. E. Lewis, , P. L. S. M. Gordts

This study shows that 3-sialyllactose reduces inflammation and atherosclerosis in mice by modulating transcriptional activity in macrophages.

bioRxiv · Mar 19, 2021Immunology

Oxidized Lipids and CD36-Mediated Lipid Peroxidation in CD8 T Cells Suppress Anti-Tumor Immune Responses

S. Xu, O. Chaudhary, P. Rodriguez-Morales, X. Sun, R. Zappasodi, Z. Xu, A. F. M. Pinto, A. Williams, D. Chen, J. S. Low, Y. Farsakoglu, W. Tang, H. Wang, S. K. Varanasi, B. McDonald, , S. M. Kaech

This study identifies CD36-mediated lipid peroxidation driven by oxidized lipids as a mechanism suppressing anti-tumor CD8 T cell functions in murine tumors.

bioRxiv · Sep 3, 2020Immunology