J. Lei

The paper reports cryo-EM structures of RyR2 bound to modulators, revealing how Ca2+ and other molecules regulate channel gating and provide insights into cardiac disorder mechanisms.

This study uses single particle cryo-EM to determine the structure of 52 kDa streptavidin at 3.2 Angstrom resolution, demonstrating the feasibility of high-resolution imaging for small molecules.

This study reports cryo-EM structures of two late-stage human spliceosomes, revealing insights into exon release and spliceosome disassembly mechanisms.

This study examines how the honey bee parasite Lotmaria passim alters its transcriptome during infection and how the host honey bee responds genetically and physiologically.

The paper identifies sensory organs and ionotropic receptors in honey bee parasitic mites, showing functional conservation with Drosophila.

The paper determines cryo-EM structures of yeast spliceosome B* complexes to elucidate the mechanism of the branching reaction during pre-mRNA splicing.

This study examines how different fruit tree shade intensities affect wheat growth, yield, and quality in intercropping systems, finding that shade reduces yield components but increases protein content and dough properties.

The paper demonstrates the use of Volta phase plate with Cs-corrected TEM to achieve near-atomic resolution structures of apo-ferritin from over-focused images.