Author

J. Luptak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Albecka· 2 shared D. Mallery· 2 shared A. P. Carter· 1 shared A. S. Fowler· 1 shared A. S. Jahun· 1 shared B. Williams· 1 shared C. Swanton· 1 shared D. Clift· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. Albecka

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TRIM7 restricts Coxsackievirus and norovirus infection by detecting the C-terminalglutamine generated by 3C protease processing

J. Luptak, D. Mallery, A. S. Jahun, A. Albecka, D. Clift, O. Ather, G. Slodkowicz, I. Goodfellow, L. James

The paper identifies TRIM7 as a viral restriction factor that recognizes a conserved C-terminal glutamine motif generated by viral proteases, inhibiting Coxsackie and norovirus replication.

bioRxiv · Jun 28, 2022Biochemistry

Emergence of new subgenomic mRNAs in SARS-CoV-2

H. V. Mears, G. R. Young, T. Sanderson, R. Harvey, M. Crawford, D. M. Snell, A. S. Fowler, S. Hussain, J. Nicod, T. P. Peacock, E. Emmott, K. Finsterbusch, J. Luptak, E. Wall, B. Williams, , D. L. Bauer

This study identifies new subgenomic mRNAs in SARS-CoV-2 arising from mutations that create novel transcription regulatory sequences, leading to the expression of functional proteins like N.iORF3.

bioRxiv · Apr 20, 2022 · PreprintMicrobiology

Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion

G. Papa, D. Mallery, A. Albecka, L. Welch, J. Cattin-Ortola, J. Luptak, D. Paul, H. T. McMahon, I. G. Goodfellow, A. P. Carter, S. Munro, L. C. James

bioRxiv · Aug 13, 2020Microbiology