Author

H. V. Mears

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

E. Emmott· 3 shared A. S. Fowler· 2 shared B. Williams· 2 shared C. Swanton· 2 shared D. L. Bauer· 2 shared J. Nicod· 2 shared R. Harvey· 2 shared S. Gandhi· 2 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

E. Emmott

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dichotomy of neutralizing antibody, B cell and T cell responses to SARS-CoV-2 vaccination and protection in healthy adults

E. J. Carr, H. Townsley, M. Y. Wu, K. A. Wilkinson, P. S. Hobson, D. Levi, S. Namjou, H. V. Mears, A. Hobbs, M. Ragno, L. S. Herman, R. Harvey, C. Bailey, A. S. Fowler, E. Hatipoglu, , E. C. Wall

The paper identifies four patterns of SARS-CoV-2 vaccine responses, including broad and narrow responders, and links broad responder traits to longer infection-free time after vaccination.

bioRxiv · May 24, 2023 · PreprintImmunology

Emergence of new subgenomic mRNAs in SARS-CoV-2

H. V. Mears, G. R. Young, T. Sanderson, R. Harvey, M. Crawford, D. M. Snell, A. S. Fowler, S. Hussain, J. Nicod, T. P. Peacock, E. Emmott, K. Finsterbusch, J. Luptak, E. Wall, B. Williams, , D. L. Bauer

This study identifies new subgenomic mRNAs in SARS-CoV-2 arising from mutations that create novel transcription regulatory sequences, leading to the expression of functional proteins like N.iORF3.

bioRxiv · Apr 20, 2022 · PreprintMicrobiology

Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells.

H. V. Mears, E. Emmott, Y. Chaudhry, M. Hosmillo, I. G. Goodfellow, T. R. Sweeney

This study shows Ifit1 enhances the interferon response but does not directly inhibit norovirus translation in murine macrophage-like cells.

bioRxiv · Apr 17, 2019Immunology

IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA.

R. C. Fleith, H. V. Mears, E. Emmott, S. C. Graham, D. S. Mansur, T. R. Sweeney

This study identifies how IFIT3 and IFIT2 enhance IFIT1's ability to inhibit translation by stabilizing its binding to non-self RNA.

bioRxiv · Feb 8, 2018Immunology