Author

J. M. Hernandez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Assay:imaging· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. J. Radtke· 2 shared E. Speranza· 2 shared J. L. Davis· 2 shared L. Yao· 2 shared R. N. Germain· 2 shared A. Bagaev· 1 shared A. C. Palmer· 1 shared A. C. R. Portela· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

A. J. Radtke

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types

J.-K. Chen, K. A. Merrick, Y. W. Kong, A. Izrael-Tomasevic, G. Eng, E. D. Handly, J. C. Patterson, L. Suarez-Lopez, A. M. Hosios, A. Dinh, D. S. Kirkpatrick, K. Yu, C. M. Rose, J. M. Hernandez, H. Hwangbo, , M. B. Yaffe

This paper shows 5-FU's lethality in tumors is due to an RNA damage response, not DNA damage, and that targeting this response could improve cancer therapy.

bioRxiv · Apr 28, 2023 · PreprintCancer Biology

A Multi-scale, Multiomic Atlas of Human Normal and Follicular Lymphoma Lymph Nodes

A. J. Radtke, E. Postovalova, A. Varlamova, A. Bagaev, M. Sorokina, O. Kudryashova, M. Meerson, M. Polyakova, I. Galkin, V. Svekolkin, S. Isaev, G. Perelman, Y. Lozinsky, Z. Yaniv, B. C. Lowekamp, , R. N. Germain

This study creates a multi-scale, multiomic atlas of human normal and follicular lymphoma lymph nodes to identify tumor-specific features and microenvironmental patterns associated with early relapse.

bioRxiv · Jun 3, 2022Cancer Biology

FECAL MICROBIOME OF CHILDREN WITH NOROVIRUS GASTROENTERITIS

J. M. Hernandez, E. C. S. Junior, G. B. S. Almeida, A. C. R. Portela, M. S. S. Lucena, J. F. Cardoso, T. K. A. Reymao, C. P. S. Lima, M. R. T. Nunes, D. M. Teixeira, J. A. M. Siqueira, Y. B. Gabbay, L. D. Silva

The paper analyzes the fecal microbiome of children with norovirus gastroenteritis, finding associations between certain bacteria and viral infections.

bioRxiv · Mar 23, 2021 · PreprintMicrobiology

IBEX: A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

A. J. Radtke, E. Kandov, B. Lowekamp, E. Speranza, C. J. Chu, A. Gola, N. Thakur, R. Shih, L. Yao, Z. R. Yaniv, R. T. Beuschel, J. Kabat, J. Croteau, J. Davis, J. M. Hernandez, R. N. Germain

IBEX enables high-resolution, multi-plex imaging of over 65 parameters in tissue sections without degradation, supporting spatial analysis and integration with other technologies.

bioRxiv · Nov 20, 2020Immunology

Single-cell atlas of tumor clonal evolution in liver cancer

L. Ma, L. Wang, C.-W. Chang, S. Heinrich, D. Dominguez, M. Forgues, J. Candia, M. O. Hernandez, M. Kelly, Y. Zhao, B. Tran, J. M. Hernandez, J. L. Davis, D. E. Kleiner, B. J. Wood, , X. W. Wang

This study constructs a single-cell atlas of liver cancer tumor clonality using machine learning and identifies osteopontin as a key driver of tumor evolution and immune reprogramming.

bioRxiv · Aug 18, 2020Cancer Biology