The transcription factors TFEB and TFE3 link the FLCN-AMPK signaling axis to innate immune response and pathogen resistance
L. El-Houjeiri, E. Possik, T. Tarika Vijayaraghavan, M. Paquette, J. A. Martina, J. M. Kazan, E. H. Ma, R. Jones, P. Blanchette, R. Puertollano, A. Pause
This study identifies a conserved mechanism linking FLCN-AMPK signaling to TFEB/TFE3 activation, enhancing innate immunity and pathogen resistance across species.
bioRxiv · Nov 6, 2018Immunology