Author

J. Manning

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Animal Behavior & Cognition· 1 Cell Biology· 1 Ecology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:mouse· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Assay:behavioral assay· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Mushala· 3 shared I. Scott· 3 shared M. Stoner· 3 shared P. Bugga· 3 shared N. Bhattarai· 2 shared A. Adams· 1 shared A. Vandevender· 1 shared B. Kaufman· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersPhysiology

B. Mushala

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

GCN5L1 inhibits pyruvate dehydrogenase phosphorylation during cardiac ischemia- reperfusion injury

P. Bugga, M. Stoner, J. Manning, B. Mushala, N. Bhattarai, M. Sharifi-Sanjani, I. Scott

This study shows that GCN5L1 loss increases pyruvate dehydrogenase phosphorylation, inhibiting glucose oxidation and worsening myocardial damage during ischemia-reperfusion injury.

bioRxiv · Jun 3, 2024Physiology

TCA Cycle Dysfunction and Amino Acid Catabolism Drive Hepatic Steatosis in Mice with HFpEF

B. Mushala, M. Stoner, J. Manning, P. Bugga, N. Bhattarai, M. Sanjani, B. McMahon, A. Vandevender, S. Mullett, B. Kaufman, S. Shiva, S. Gelhaus, M. Jurczak, I. Scott

This study shows that TCA cycle dysfunction and amino acid catabolism in mice with HFpEF drive hepatic steatosis similar to human NAFLD.

bioRxiv · Jun 3, 2024 · PreprintPhysiology

Validation of GCN5L1/BLOC1S1/BLOS1 Antibodies Using Knockout Cells and Tissue

P. Bugga, M. Stoner, J. Manning, B. Mushala, D. Thapa, I. Scott

The paper validates GCN5L1 antibodies using knockout cells and tissue, finding that two-thirds of commercially available antibodies fail to reliably detect the protein.

bioRxiv · Jul 21, 2023Cell Biology

Therapeutic immunization with a whole cell vaccine reduces pneumococcal nasopharyngeal density, shedding, and middle ear infection in mice

J. Manning, S. Manna, E. M. Dunne, V. Bongcaron, C. Pell, N. L. Patterson, S. D. Kuil, P. Dhar, D. Goldblatt, E. K. Mulholland, P. V. Licciardi, R. M. Robins-Browne, R. Malley, O. Wijburg, C. Satzke

bioRxiv · Apr 5, 2023Microbiology

A model of preferential pairing between epithelial and dendritic cells in thymic antigen transfer

D. Filipp, R. S. Blumberg, M. Voboril, J. Brezina, T. Brabec, J. Dobes, O. Ballek, J. Manning, M. Dobesova

The paper investigates preferential pairing between thymic epithelial cells and dendritic cells in antigen transfer, finding that specific DC subsets preferentially acquire antigens from specific mTEC subsets.

bioRxiv · Sep 13, 2021Immunology

Ungulate Responses to Unmanned Aerial Vehicles Flying at Different Altitudes in Africas Arid Savanna

M. van Vuuren, R. van Vuuren, L. Silverberg, J. Manning, K. Pacifici, W. Dorgeloh, J. Campbell

This study examines how different flight altitudes of UAVs affect the behavioral responses of various ungulates in Namibia's arid savanna, finding strong correlations between altitude and response with some habituation observed.

bioRxiv · Jul 14, 2020 · PreprintAnimal Behavior & Cognition

On simulating cold stunned turtle strandings on Cape Cod

X. Liu, J. Manning, R. Prescott, H. Zou, M. Faherty

This study investigates the causes of increased cold-stunned Kemp's ridley turtle strandings on Cape Cod using ocean models and observations.

bioRxiv · Feb 20, 2019Ecology

The chemistry and pharmacology of putative synthetic cannabinoid receptor agonist (SCRA) new psychoactive substances (NPS) 5F-PY-PICA, 5F-PY-PINACA, and their analogues

S. Banister, R. Kevin, L. Martin, A. Adams, C. Macdonald, J. Manning, B. Rochelle, C. Michael, M. Stevens, I. McGregor, M. Glass, M. Connor, R. Gerona

This study synthesizes and characterizes new psychoactive substances (NPS) and evaluates their pharmacology at cannabinoid receptors.

bioRxiv · Oct 3, 2018Pharmacology & Toxicology