Author

S. Manna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 6 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

C. Satzke· 4 shared E. K. Mulholland· 4 shared E. M. Dunne· 3 shared A. Shivashankar· 2 shared B. D. Ortika· 2 shared B. S. Choudhary· 2 shared C. L. Pell· 2 shared J. Hinds· 2 shared

Activity by Year

2018-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersMicrobiology

C. Satzke

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Modulation of H3K4 trimethylation by KDM5A and MLLs impacts metabolic adaptability in prostate and cervical cancer cells

K. R, S. Manna, S. K. Patra

This study shows that KDM5A and MLLs modulate metabolic adaptability in prostate and cervical cancer cells by regulating H3K4me3 levels on metabolic gene promoters.

bioRxiv · May 2, 2024 · PreprintCancer Biology

Osteopontin in colitis-associated carcinoma

S. Manna, M. Sehn, D. Cardoso da Silva, J. J. Wiese, C. Heldt, I. Plumbom, T. Conrad, C. C. Husemann, K. Kleo, L. Derezanin, V. Dony, S. K. Farahani, F. Weiss, A. A. Kuehl, S. Schallenberg, , M. Schumann

This study investigates the role of osteopontin (SPP1/OPN) in colitis-associated carcinoma (CAC) using a multi-omics approach, revealing its indirect immunosuppressive role in the tumor microenvironment.

bioRxiv · Dec 15, 2023 · PreprintCancer Biology

Streptococcus pneumoniae serotype 33G: genetic, serological, and structural analysis of a new capsule type

S. Manna, J. P. Werren, B. D. Ortika, B. Bellich, C. L. Pell, E. Nikolaou, I. Gjuroski, S. W. Lo, J. Hinds, O. Tundev, E. M. Dunne, B. D. Gessner, S. D. Bentley, F. Russell, E. K. Mulholland, , C. Satzke

This study identifies and characterizes a new Streptococcus pneumoniae serotype, 33G, through genetic, serological, and structural analysis of isolates from Mongolia.

bioRxiv · Sep 11, 2023 · PreprintMicrobiology

EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI

N. Chaudhary, B. S. Choudhary, A. Shivashankar, S. Manna, K. Ved, S. E. Shaikh, S. Khanna, J. Barr, J. Dani, N. Verma

This study identifies a hyper-phosphorylation state in drug-resistant TNBC cells caused by EGFR-to-Src kinase switching, making them vulnerable to EGFR TKI treatment.

bioRxiv · Jul 17, 2023Cancer Biology

GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition.

N. Chaudhary, B. S. Choudhary, S. Patra, S. Malvankar, A. Shivashankar, E. Jog, V. K. Kailaje, S. Khanna, S. Manna, S. Sahoo, S. R, M. K. Jolly, S. N. Dalal, N. Verma

The paper identifies a proliferating DTP state in TNBC subtypes that is vulnerable to autophagy and glutathione inhibition, linking GPX4-VIM expression to survival outcomes.

bioRxiv · May 18, 2023 · PreprintCancer Biology

Therapeutic immunization with a whole cell vaccine reduces pneumococcal nasopharyngeal density, shedding, and middle ear infection in mice

J. Manning, S. Manna, E. M. Dunne, V. Bongcaron, C. Pell, N. L. Patterson, S. D. Kuil, P. Dhar, D. Goldblatt, E. K. Mulholland, P. V. Licciardi, R. M. Robins-Browne, R. Malley, O. Wijburg, C. Satzke

bioRxiv · Apr 5, 2023Microbiology

Synergism and antagonism of bacterial-viral co-infection in the upper respiratory tract

S. Manna, J. McAuley, J. Jacobson, C. D. Nguyen, M. A. Ullah, V. Williamson, E. K. Mulholland, O. Wijburg, S. Phipps, C. Satzke

This study investigates bacterial-viral co-infection dynamics in the upper respiratory tract, finding both synergistic and antagonistic effects between pneumococci and RSV-like viruses.

bioRxiv · Nov 11, 2020 · PreprintMicrobiology

Discovery of a Streptococcus pneumoniae serotype 33F capsular polysaccharide locus that lacks wcjE and contains a wcyO pseudogene

S. Manna, E. M. Dunne, B. D. Ortika, C. L. Pell, M. Kama, F. M. Russell, T. Mungun, E. K. Mulholland, J. Hinds, C. Satzke

The paper identifies a novel variant of Streptococcus pneumoniae serotype 33F lacking wcjE and containing a wcyO pseudogene, highlighting genetic diversity in pneumococcal serotypes.

bioRxiv · May 17, 2018Microbiology