Author

J. Martinez-Picado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 2 Organism:human· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1 Assay:imaging· 1 Assay:metagenomics· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

N. Izquierdo-Useros· 3 shared B. Clotet· 2 shared M. Noguera-Julian· 2 shared R. Paredes· 2 shared A. Borgognone· 1 shared A. Burgener· 1 shared A. Telenti· 1 shared B. Mothe· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

N. Izquierdo-Useros

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Actin-regulated Siglec-1 nanoclustering influences HIV-1 capture and virus-containing compartment formation in dendritic cells

M. F. Garcia-Parajo, E. Gutierrez-Martinez, S. Benet Garrab, N. Mateos, I. Erkiziac, J. A. Nieto-Garai, M. Lorizate, C. Manzo, F. Campelo, N. Izquierdo-Useros, J. Martinez-Picado

This study shows that actin-regulated Siglec-1 nanoclustering in activated dendritic cells enhances HIV-1 capture and trafficking into a single viral-containing compartment.

bioRxiv · Apr 28, 2022Cell Biology

Gut Microbiome Signatures Linked to HIV-1 Reservoir Size and Viremia Control

A. Borgognone, M. Noguera-Julian, B. Oriol, L. Noël-Romas, M. Ruiz-Riol, Y. Guillen, M. Parera, M. Casadella, C. Duran, M. C. Puertas, F. Catala-Moll, M. De Leon, S. Knodel, K. Birse, C. Manzardo, , R. Paredes

The paper identifies gut microbiome signatures, specifically the Bacteroidales/Clostridiales ratio, associated with HIV-1 reservoir size and viremia control in a clinical trial.

bioRxiv · Oct 3, 2021Immunology

Siglec-1 on dendritic cells mediates SARS-CoV-2 trans-infection of target cells while on macrophages triggers proinflammatory responses

D. Perez-Zsolt, J. Munoz Basagoiti, J. Rodo, M. Elousa, D. Raich Regue, C. Risco, M. Sachse, M. Pino, S. Gumber, M. Paiardini, J. Chojnacki, I. Erkizia, X. Muniz, E. Ballana, E. Riveira Munoz, , N. Izquierdo-Useros

This study shows Siglec-1 on APCs mediates SARS-CoV-2 trans-infection and triggers proinflammatory responses, suggesting it as a potential therapeutic target.

bioRxiv · May 11, 2021 · PreprintMicrobiology

Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages

C. Verollet, M. Dupont, S. Souriant, L. Balboa, T. Phong, K. Pingris, S. Rousset, C. Cougoule, Y. Romboust, R. Poincloux, M. Ben Neji, C. Allers, D. Kaushal, M. J. Kuroda, S. Benet, , G. Lugo-Villarino

This study identifies Siglec-1 as a factor induced by TB-associated IFN-I that localizes on TNTs and promotes HIV-1 spread in macrophages.

eLife · Mar 30, 2020Peer-reviewedCell Biology