Author

J. McLeod

University of British Columbia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Neuroscience· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Research Focus:cell type annotation· 5 Approach:statistical model· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Assay:electronic health records· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

J. E. Dick· 3 shared A. Chavan· 2 shared E. Wagenblast· 2 shared L. Jin· 2 shared Naznin Virji‐BabuliD· 2 shared Sahar SattariiD· 2 shared A. Arruda· 1 shared A. Bashir· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCell Biology

J. E. Dick

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Author profile →

6 papers

Recent·Most cited

FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells

J. L. Araujo, E. Wagenblast, V. Voisin, J. McLeod, O. I. Gan, S. Bansal, L. Jin, A. Mitchell, B. Gratton, S. Cutting, A. Arruda, M. Doedens, J.-M. Capo-Chichi, S. Abelson, M. D. Minden, , J. E. Dick

This study shows FLT3 is essential for ITD-mutated leukemic stem cells but not for normal hematopoietic stem cells, supporting targeted therapies for AML.

bioRxiv · Jun 30, 2024Cancer Biology

Menstrual cycle phase modulates causal connectivity in the resting-state brain of healthy females.

J. Mcleod, Sahar Sattari, A. Chavan, Liisa A.M. Galea, Shazia’Ayn Babul, Naznin Virji‐Babul

This study examines how menstrual cycle phases affect resting-state brain connectivity in healthy females, finding distinct patterns in causal connectivity linked to hormone levels.

bioRxiv · Jun 7, 2024 · PreprintNeuroscience

Distinct effects of priming the brain using tDCS and observational practice: new evidence from brain effective connectivity.

J. McLeod, A. Chavan, H. Lee, Sahar Sattari, Simrut Kurry, Melissa A Wake, Zia Janmohamed, Nicola J. Hodges, Naznin Virji‐Babul

This study compares the effects of tDCS and observational practice on bimanual coordination, finding higher juggling scores with observation and distinct brain connectivity patterns.

bioRxiv · Dec 12, 2023 · PreprintNeuroscience

Identification of a human hematopoietic stem cell subset that retains memory of inflammatory stress

A. G. X. Zeng, M. S. Nagree, N. A. Jakobsen, S. Shah, A. Murison, J.-G. Cheong, S. Turkalj, I. Lim, L. Jin, J. Araujo, A. G. Aguilar-Navarro, D. Parris, J. McLeod, H. Kim, H. S. Lee, , S. Z. Xie

The paper identifies a human HSC subset with inflammatory memory that accumulates with age and clonal hematopoiesis, potentially increasing cancer and infection risks.

bioRxiv · Sep 11, 2023 · PreprintCell Biology

Adaptation to ex vivo culture drives human haematopoietic stem cell loss of repopulation capacity in a cell cycle independent manner

C. S. Johnson, K. Sham, S. Belluschi, X. Wang, W. Lau, K. B. Kaufmann, G. Krivdova, E. F. Calderbank, N. Mende, J. McLeod, G. Mantica, M. J. Williams, C. Grey-Wilson, M. Drakopoulos, S. Sinha, , E. Laurenti

This study shows that human LT-HSC loss of repopulation capacity during ex vivo culture occurs rapidly after adaptation, independent of cell cycle progression.

bioRxiv · Nov 17, 2022 · PreprintCell Biology

Effects of High-Volume versus High-Load Resistance Training on Skeletal Muscle Growth and Molecular Adaptations

C. Vann, C. Sexton, S. Osburn, M. Smith, C. Haun, M. Rumbley, P. Mumford, B. Ferguson, N. Montgomery, C. Fox, B. Ruple, J. McKendry, J. McLeod, A. Bashir, R. Beyers, , M. Roberts

This study compares high-volume and high-load resistance training on muscle growth and molecular markers, finding similar hypertrophic and strength adaptations despite differences in protein synthesis rates.

bioRxiv · Jul 1, 2021Physiology