Author

J. N. Engel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

R. Patino· 3 shared Y. Inclan· 3 shared A. Persat· 2 shared H. Macmillan· 2 shared L. Tala· 2 shared X. Pierrat· 2 shared Z. Al-Mayyah· 2 shared A. D. Grossman· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

R. Patino

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pseudomonas aeruginosa mechanosensing controls cell polarity during twitching by activating two antagonistic response regulators

M. J. Kuhn, H. Macmillan, L. Tala, Y. Inclan, R. Patino, X. Pierrat, Z. Al-Mayyah, J. N. Engel, A. Persat

This study identifies how two response regulators, PilG and PilH, control cell polarity in Pseudomonas aeruginosa during twitching motility by antagonistically responding to mechanosensing signals.

bioRxiv · Nov 15, 2022Microbiology

Mechanotaxis directs Pseudomonas aeruginosa twitching motility.

L. Tala, M. Kuhn, Y. Inclan, R. Patino, X. Pierrat, I. Vos, Z. Al-Mayyah, H. MacMillan, J. Negrete, J. N. Engel, A. Persat

This study identifies mechanotaxis as the mechanism by which Pseudomonas aeruginosa directs twitching motility using the Chp system to control directional migration.

bioRxiv · Jan 26, 2021Microbiology

Mobile-CRISPRi: Enabling Genetic Analysis of Diverse Bacteria

J. M. Peters, B.-M. Koo, R. Patino, G. E. Heussler, C. C. Hearne, Y. Inclan, J. S. Hawkins, C. H. S. Lu, M. M. Harden, H. Osadnik, J. E. Peters, J. N. Engel, R. J. Dutton, A. D. Grossman, C. A. Gross, O. S. Rosenberg

The paper introduces Mobile-CRISPRi, a CRISPRi system for non-model bacteria, demonstrating its use in analyzing gene function and antibiotic resistance in human pathogens.

bioRxiv · May 5, 2018Microbiology