Author

L. Tala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:bacteria (other)· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Persat· 5 shared H. Macmillan· 2 shared J. N. Engel· 2 shared R. Patino· 2 shared X. Pierrat· 2 shared Y. Inclan· 2 shared Z. Al-Mayyah· 2 shared A. Fineberg· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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5 shared papersMicrobiology

A. Persat

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Archaeal type IV pili stabilize Haloferax volcanii biofilms in flow

P. Odermatt, P. Nussbaum, S. Monnappa, L. Tala, Z. Li, S. Sivabalasarma, S.-V. Albers, A. Persat

This study shows that type IV pili in Haloferax volcanii are essential for biofilm stability under flow, with PilA2 sufficient for normal biofilm structure.

bioRxiv · Jan 20, 2023 · PreprintMicrobiology

Pseudomonas aeruginosa mechanosensing controls cell polarity during twitching by activating two antagonistic response regulators

M. J. Kuhn, H. Macmillan, L. Tala, Y. Inclan, R. Patino, X. Pierrat, Z. Al-Mayyah, J. N. Engel, A. Persat

This study identifies how two response regulators, PilG and PilH, control cell polarity in Pseudomonas aeruginosa during twitching motility by antagonistically responding to mechanosensing signals.

bioRxiv · Nov 15, 2022Microbiology

Pseudomonas aeruginosa contracts mucus to form biofilms in tissue-engineered human airways

T. Rossy, T. Distler, J. Pezoldt, J. Kim, L. Tala, N. Bouklas, B. Deplancke, A. Persat

This study shows Pseudomonas aeruginosa forms mucus-associated biofilms in human airway models by contracting mucus using type IV pili.

bioRxiv · May 26, 2022 · PreprintMicrobiology

Mechanotaxis directs Pseudomonas aeruginosa twitching motility.

L. Tala, M. Kuhn, Y. Inclan, R. Patino, X. Pierrat, I. Vos, Z. Al-Mayyah, H. MacMillan, J. Negrete, J. N. Engel, A. Persat

This study identifies mechanotaxis as the mechanism by which Pseudomonas aeruginosa directs twitching motility using the Chp system to control directional migration.

bioRxiv · Jan 26, 2021Microbiology

Label-free visualization of type IV pili dynamics by interferometric scattering microscopy

L. Tala, A. Fineberg, P. Kukura, A. Persat

This study uses interferometric scattering microscopy to visualize type IV pili dynamics in Pseudomonas aeruginosa, revealing crawling behavior and rapid retraction after surface attachment.

bioRxiv · Apr 10, 2018Microbiology