Author

J. Nian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

X. ZhangiD· 2 shared Z. WangiD· 2 shared A. Zhu· 1 shared C. Li· 1 shared D. Zhang· 1 shared F. Zhang· 1 shared H. Zhao· 1 shared J. Chen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

X. ZhangORCID

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Author profile →

2 papers

Recent·Most cited

Senolytics enhance longevity in Caenorhabditis elegans by altering betaine metabolism

W. Lan, X. Xiao, X. Zhang, J. Nian, Z. Wang, Y. Wu, D. Zhang, J. Chen, W. Bao, C. Li, A. Zhu, Y. Zhang, F. Zhang

This study identifies betaine metabolism as a key factor in aging in C. elegans and shows that senolytics extend lifespan by increasing betaine levels and enhancing autophagy and antioxidant capacity.

bioRxiv · Dec 19, 2023 · PreprintBiochemistry

Rottlerin ameliorates DSS-induced colitis by improving intestinal barrier function via activation of the Epac-2/Rap-1 signaling pathway.

X. Song, L. Zuo, L. Wang, Z. Zhu, J. Tao, Y. Jiang, X. Wu, Z. Wang, J. Nian, P. Xiang, X. Zhang, H. Zhao, L. Yu, J. Li, J. Hu

This study shows rottlerin reduces DSS-induced colitis in mice by enhancing intestinal barrier function through the Epac-2/Rap-1 signaling pathway.

bioRxiv · Mar 16, 2020 · PreprintCell Biology