Author

A. Shilatifard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Assay:ChIP-seq· 2 Assay:flow cytometry· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Bharat· 2 shared A. V. Misharin· 2 shared G. S. Budinger· 2 shared H. Abdala-Valencia· 2 shared M.-C. Keogh· 2 shared N. S. Markov· 2 shared R. A. Grant· 2 shared S. Swaminathan· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Bharat

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal

W. J. Cisneros, M. Walter, S. H. A. Soliman, L. M. Simons, D. Cornish, A. W. Halle, E.-Y. Kim, S. M. Wolinsky, A. Shilatifard, J. F. Hultquist

This paper shows that inhibiting the Super Elongation Complex (SEC) with KL-2 increases HIV-1 transcription and reactivates latent virus, especially when combined with other latency reversing agents.

PLOS Pathogens · Sep 11, 2024Peer-reviewedMicrobiology

Expansion of profibrotic monocyte-derived alveolar macrophages in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19

J. I. Bailey, C. H. Puritz, K. J. Senkow, N. S. Markov, E. Diaz, E. Jonasson, Z. Yu, S. Swaminathan, Z. Lu, S. Fenske, R. A. Grant, H. Abdala-Valencia, R. J. Mylvaganam, J. Miller, R. I. Cumming, , M. A. Sala

The paper identifies profibrotic monocyte-derived alveolar macrophages and neutrophil recruitment as drivers of lung fibrosis in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19.

bioRxiv · Jul 30, 2023Immunology

Alveolitis in severe SARS-CoV-2 pneumonia is driven by self-sustaining circuits between infected alveolar macrophages and T cells

R. A. Grant, L. Morales-Nebreda, N. S. Markov, S. Swaminathan, E. R. Guzman, D. A. Abbott, H. K. Donnelly, A. Donayre, I. A. Goldberg, Z. M. Klug, N. Borkowski, Z. Lu, H. Kihshen, Y. Politanska, L. Sichizya, , The NU SCRIPT Study Investigators

The paper identifies a positive feedback loop between SARS-CoV-2-infected alveolar macrophages and T cells in severe COVID-19 patients, driving persistent alveolitis.

Nature · Jan 11, 2021Peer-reviewedImmunology

Decoding the Protein Composition of Whole Nucleosomes with Nuc-MS

L. F. Schachner, K. Jooss, M. A. Morgan, A. Piunti, M. J. Meiners, A. Lee, J. O. Kafader, M. Iwanaszko, M. A. Cheek, J. M. Burg, S. A. Howard, M.-C. Keogh, A. Shilatifard, N. L. Kelleher

The paper introduces Nuc-MS, a method to analyze protein composition of whole nucleosomes, revealing specific histone variants and modifications associated with oncogenic states.

bioRxiv · Sep 8, 2020Biochemistry

A ChIP-exo screen of 887 PCRP transcription factor antibodies in human cells

W. K. Lai, L. Mariani, G. Rothschild, E. R. Smith, B. J. Venters, T. R. Blanda, P. K. Kuntala, K. Bocklund, J. Mairose, S. N. Dweikat, K. Mistretta, M. J. Rossi, D. James, J. T. Anderson, S. K. Phanor, , B. F. Pugh

The paper evaluates 887 PCRP antibodies against human transcription factors using ChIP-exo and other assays, identifying 5% as strong candidates and 34% as warranting further testing.

bioRxiv · Jun 8, 2020Biochemistry