Author

J. Q. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1

Frequent Co-Authors

G. Wang· 2 shared L. Huang· 2 shared O. Verdejo-Torres· 2 shared X.-O. Zhang· 2 shared A. D. Durbin· 1 shared B. Sallis· 1 shared C. A. Cuomo· 1 shared C. Dong· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

G. Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PRMT5 orchestrates EGFR and AKT networks to activate NFκB and promote EMT

L. Huang, M. Ravi, X.-O. Zhang, O. Verdejo-Torres, N. A. M. Shendy, M. A. M. Nezhady, S. Gopalan, G. Wang, A. D. Durbin, T. G. Fazzio, J. Q. Wu

This study identifies PRMT5's role in promoting EMT in neuroblastoma by regulating EGFR and AKT pathways, leading to NFκB activation and tumor growth.

bioRxiv · Jan 3, 2024 · PreprintCancer Biology

Protein arginine methyltransferase 5 promotes metastasis via enhancing EGFR transcription and modulating AKT1 activation by methylation

L. Huang, X.-O. Zhang, O. Verdejo-Torres, K. Wigglesworth, X. Sun, B. Sallis, D. Moon, T. Huang, E. Rozen, L. Zhang, G. Wang, J. M. Shohet, M. M. Lee, J. Q. Wu

This study shows PRMT5 promotes cancer metastasis by enhancing EGFR transcription and modulating AKT1 activation through methylation, leading to EMT and tumor cell invasion.

bioRxiv · Aug 12, 2020 · PreprintCancer Biology

Dissecting the first phased dikaryotic genomes of the wheat rust pathogen Puccinia triticina reveals the mechanisms of somatic exchange in nature

J. Q. Wu, C. Dong, L. Song, C. A. Cuomo, R. F. Park

This study generates and analyzes the first dikaryotic phased genomes of Puccinia triticina, identifying a somatic hybrid and revealing mitotic crossover as the mechanism of parasexuality in rust pathogens.

bioRxiv · Jul 17, 2019 · PreprintMicrobiology