Author

J. R. Gatdula

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Microbiology· 1

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Organism:C. elegans· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

E. M. Lewandowski· 1 shared J. A. Townsend· 1 shared J. Wang· 1 shared L. R. Hammond· 1 shared M. D. Sacco· 1 shared M. T. Marty· 1 shared M. V. Gongora· 1 shared P. J. Eswara· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

E. M. Lewandowski

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1 paper

Recent·Most cited

A unique class of Zn2+-binding PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile

M. D. Sacco, S. Wang, S. R. Adapa, X. Zhang, M. V. Gongora, J. R. Gatdula, E. M. Lewandowski, L. R. Hammond, J. A. Townsend, M. T. Marty, J. Wang, P. J. Eswara, R. H. Y. Jiang, X. Sun, Y. Chen

This study identifies PBP2 as the primary target of cephalosporins in C. difficile and reveals a unique Zn2+-binding motif in PBP2 and related PBPs that contributes to cephalosporin resistance and sporulation.

bioRxiv · Jan 4, 2022 · PreprintMicrobiology