Author

L. R. Hammond

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

M. D. Sacco· 3 shared P. J. Eswara· 3 shared Y. Chen· 3 shared S. J. Khan· 2 shared A. C. Jaskolka-Brown· 1 shared A. Hough· 1 shared C. Spanoudis· 1 shared D. Bhattacharya· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

M. D. Sacco

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB

M. D. Sacco, L. R. Hammond, R. E. Noor, D. Bhattacharya, J. J. Madsen, X. Zhang, S. G. Butler, M. T. Kemp, A. C. Jaskolka-Brown, S. J. Khan, I. Gelis, P. J. Eswara, Y. Chen

This study determines the structure of S. aureus GpsB's N-terminal domain, revealing its interaction with FtsZ and PBP4, and shows its essential role in cell division.

bioRxiv · Oct 25, 2022Microbiology

A unique class of Zn2+-binding PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile

M. D. Sacco, S. Wang, S. R. Adapa, X. Zhang, M. V. Gongora, J. R. Gatdula, E. M. Lewandowski, L. R. Hammond, J. A. Townsend, M. T. Marty, J. Wang, P. J. Eswara, R. H. Y. Jiang, X. Sun, Y. Chen

This study identifies PBP2 as the primary target of cephalosporins in C. difficile and reveals a unique Zn2+-binding motif in PBP2 and related PBPs that contributes to cephalosporin resistance and sporulation.

bioRxiv · Jan 4, 2022 · PreprintMicrobiology

GpsB coordinates cell division and cell surface decoration by wall teichoic acids in Staphylococcus aureus

L. R. Hammond, S. J. Khan, M. D. Sacco, C. Spanoudis, A. Hough, Y. Chen, P. J. Eswara

This study identifies GpsB's role in coordinating cell division and wall teichoic acid biosynthesis in Staphylococcus aureus through interactions with PBPs and the WTA export complex.

bioRxiv · Sep 29, 2021Microbiology