Author

J. S. Craig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

L. Melidis· 2 shared M. J. Hannon· 2 shared R. T. Egan· 2 shared A. A. Heidecker· 1 shared A. Casini· 1 shared A. Garai· 1 shared A. Poethig· 1 shared B. Aikman· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

L. Melidis

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Organometallic Pillarplexes that bind DNA 4-way Holliday Junctions and Forks.

J. S. Craig, L. Melidis, H. D. Williams, S. J. Dettmer, A. A. Heidecker, P. J. Altmann, S. Guan, C. Campbell, D. F. Browning, R. K. O. Sigel, S. Johannsen, R. T. Egan, B. Aikman, A. Casini, A. Poethig, M. J. Hannon

This paper demonstrates that Au pillarplexes bind open DNA 4-way junctions and rearrange them into Y-shaped forks, with antiproliferative activity in human cells.

bioRxiv · Jan 4, 2023Biochemistry

Supramolecular cylinders target bulge structures in the 5-prime UTR of the RNA genome of SARS-CoV-2 and inhibit viral replication

L. Melidis, H. J. Hill, N. J. Coltman, S. P. Davies, K. Winczura, T. Chauhan, J. S. Craig, A. Garai, C. A. J. Hooper, R. T. Egan, J. A. McKeating, N. J. Hodges, Z. Stamataki, P. Grzechnik, M. J. Hannon

The paper models the 5' UTR structure of SARS-CoV-2 and shows supramolecular cylinders bind to a bulge and junction, inhibiting viral replication.

bioRxiv · Mar 30, 2021Biochemistry