Author

J. W. Pollard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

L. Cassetta· 2 shared S. J. Jenkins· 2 shared A. Robinson· 1 shared A. W. Horne· 1 shared B. E. Henderson· 1 shared B.-Z. Qian· 1 shared C. A. Rodriguez-Tirado· 1 shared C. Hogg· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCancer Biology

L. Cassetta

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Interleukin 4 controls the role of macrophages in pulmonary metastatic tumor cell seeding and growth

C. A. Rodriguez-Tirado, D. Entenberg, J. Li, B.-Z. Qian, J. S. Condeelis, J. W. Pollard

This study shows that IL4 signaling in macrophages promotes lung metastasis by enhancing tumor cell extravasation and regulating pro-tumoral gene expression.

bioRxiv · Dec 28, 2021 · PreprintCancer Biology

Systemic influences of mammary cancer on monocytes in mice

A. Robinson, M. Burgess, S. Webb, P. Louwe, Z. Ouyang, D. Skola, C. Z. Han, N. N. Batada, V. Gonzalez, L. Cassetta, C. K. Glass, S. J. Jenkins, J. W. Pollard

This study shows that mammary cancer in mice increases circulating and splenic monocytes without altering their ratios or half-lives, but changes their transcriptome, particularly in the bone marrow and blood, with differences from human breast cancer.

bioRxiv · Dec 24, 2021Cancer Biology

Macrophages can inhibit and enhance endometriosis depending on their origin

C. Hogg, P. Dhami, M. Rosser, M. Mack, D. Soong, J. W. Pollard, S. J. Jenkins, A. W. Horne, E. Greaves

This study shows that macrophages in endometriosis lesions can either promote or suppress disease depending on their origin, with eutopic endometrial macrophages being pro-endometriosis and recruited monocyte-derived macrophages being anti-endometriosis.

bioRxiv · Apr 30, 2020Immunology

Mouse Classical and Non-Classical Monocytes Express Comparable Levels of Chemokine Receptor CX3CR1

L. Cassetta, E. Heideveld, G. Matilionyte, S. Fragkogianni, E. Van den akker, N. Kippen, T. Kitamura, J. W. Pollard

This study shows that Cx3cr1 mRNA expression differs between circulating monocytic subsets in humans but not in mice.

bioRxiv · Apr 10, 2020 · PreprintImmunology

Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomics

P. Ramachandran, R. Dobie, J. R. Wilson-Kanamori, E. F. Dora, B. E. Henderson, R. S. Taylor, K. P. Matchett, J. R. Portman, M. Efremova, R. Vento-Tormo, N. T. Luu, C. J. Weston, P. N. Newsome, E. M. Harrison, D. J. Mole, , N. C. Henderson

This study uses single-cell transcriptomics to identify novel fibrotic cell types and interactions in human liver cirrhosis, revealing potential therapeutic targets.

Nature · Oct 9, 2019Peer-reviewedImmunology