T. Kitamura

Latent mitotic vulnerability of AML cells induced by therapeutic agents

This study identifies mitotic vulnerabilities in AML cells induced by therapeutic agents, showing increased cytotoxicity during mitosis compared to S/G2 phase arrest.

Social transmission of valence-linked new knowledge without firsthand experience in mice

This study introduces an improved social learning test in mice that allows learning of valence-linked knowledge without firsthand experience, showing differential hippocampal involvement in learning and recall.

TLR7/8 stress response drives histiocytosis in SLC29A3 disorders

This study identifies TLR7/8 as drivers of histiocytosis in SLC29A3 disorders by responding to lysosomal nucleoside stress and enhancing monocyte proliferation and phagocyte maturation.

Isolation of bat sarbecoviruses of SARS-CoV-2 clade, Japan

The paper isolates and characterizes SARS-CoV-2 clade sarbecoviruses from Japanese bats, showing host-specific replication and genetic variation in the S1 region.

Prospective isolation of mouse and human hematopoietic stem cells using Plexin domain containing 2

This study identifies PLXDC2 as a marker for isolating hematopoietic stem cells (HSCs) in both mouse and human, showing its utility in transplantation and xenograft models.

Mouse Classical and Non-Classical Monocytes Express Comparable Levels of Chemokine Receptor CX3CR1

This study shows that Cx3cr1 mRNA expression differs between circulating monocytic subsets in humans but not in mice.