TOMM40 suppression promotes neuronal cholesterol imbalance and molecular and behavioral phenotypes of Alzheimer's disease
Neil Victor Yang, Shaowei Wang, Boyang Li, Jeffrey A. Simms, Linsey Dinh, Annie Huang, Jacob H Oei, Hussein N. Yassine, Ronald M. Krauss
This study shows that TOMM40 suppression leads to cholesterol imbalance and AD-like molecular and behavioral changes in mice and human neurons.
Alzheimer s & Dementia · Apr 1, 2026Peer-reviewedMolecular Biology