Author

Jonatan Caroli

University of Pavia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea MatteviiD· 2 shared André MateusiD· 1 shared Ángel RomániD· 1 shared Anna Aakula· 1 shared Carlos Antonio García-PrietoiD· 1 shared Carlos Martinez‐GameroiD· 1 shared Cong Lyu· 1 shared Damiana Álvarez‐ErricoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Andrea MatteviORCID

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2 papers

Recent·Most cited

LSD1 serine 166 is a phosphorylation switch for chromatinlandscaping, gene activation, and tissue remodeling

Mukund Sharma, Anna Aakula, Oxana V. Denisova, Elena Ceccacci, Kourosh Hayatigolkhatmi, Jonatan Caroli, Reetta Nätkin, Marie-Catherine Laisne, Riikka Huhtaniemi, Sujan Ghimire, Johannes A. M. Merilahti, Roberta Noberini, Jesse Kamila, Otto Kauko, Andrea Mattevi, , Jukka K. Westermarck

This paper identifies S166 phosphorylation on LSD1 as a regulatory switch that controls gene activation, chromatin remodeling, and tumor microenvironment in non-hormonal cancer cells.

bioRxiv · May 14, 2025 · PreprintGenomics

The catalytic-independent function of LSD1 modulates the epigenetic landscape of mouse embryonic stem cells

Sandhya Malla, Kanchan Kumari, Carlos Martinez‐Gamero, Carlos Antonio García-Prieto, Stephanie Stransky, Jonatan Caroli, Damiana Álvarez‐Errico, Paulina Avovome Saiki, Weiyi Lai, Cong Lyu, Jonathan D. Gilthorpe, Hailin Wang, Simone Sidoli, Andrea Mattevi, André Mateus, , Francesca Aguiló

This study shows that LSD1's non-catalytic function regulates DNA methylation in mouse ESCs by controlling UHRF1 and DNMT1 stability through USP7 interaction.

bioRxiv · Jun 29, 2023 · PreprintMolecular Biology