Joseph van Batenburg‐Sherwood

The paper validates chip-grown vascular tissues as a model for studying vasculature by showing cell provenance affects network formation and transcriptomic profiles.

This study shows that Piezo1 signaling is influenced by force magnitude, mechanical history, and actin coupling under fluid shear, using a genetically encoded reporter in engineered cells.

This study develops an organ-on-chip model to investigate respiratory-vascular interactions under oxidative stress, revealing how airway injury drives vascular inflammation and remodeling in COPD.

This study shows corticosteroids increase intraocular pressure by suppressing TREK-1 channels in trabecular meshwork cells, leading to ocular hypertension, which can be counteracted by TREK-1 agonists.

This paper develops a thrombus-on-chip model with endothelium and whole blood to study thrombosis, showing TNF-activation increases platelet adhesion and fibrin deposition.

This study examines how aging affects intraocular pressure regulation in mice, finding that outflow facility remains stable despite age-related tissue changes.