Author

Jung Bum Shin

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ah Reum KimiD· 1 shared Aida Nourbakhsh· 1 shared Aiying ZhangiD· 1 shared Alev ErişiriD· 1 shared Allison Tucker· 1 shared Bong Jik KimiD· 1 shared Byung Yoon ChoiiD· 1 shared Changjoon Justin LeeiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Ah Reum KimORCID

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2 papers

Recent·Most cited

Modeling Alzheimer's Disease with APOE4 Neuron-Glial Brain Assembloids Reveals IGFBPs as Therapeutic Targets

Eliana Sherman, Kevin Qiu, Rebecca Roberts, Lucille Shichman, Sihan Li, Huayu Sun, Lucie Ide, Allison Tucker, Seonjoo Lee, Weronika Gniadzik, Jung Bum Shin, Katia Sol‐Church, Jaideep Kapur, Aiying Zhang, Alev Erişir, , the Alzheimer’s Disease Neuroimaging Initiative

The paper develops a 3D brain assembloid model to study Alzheimer's disease progression and identifies IGFBP pathways as therapeutic targets in APOE4 carriers.

bioRxiv · Oct 17, 2025 · PreprintNeuroscience

Mutations in TMEM43 cause autosomal dominant auditory neuropathy spectrum disorder via interaction with Connexin-mediated passive conductance channels

Minwoo Wendy Jang, Doo‐Yi Oh, Eunyoung Yi, Xuezhong Liu, Jie Ling, Nayoung Kim, Kushal Sharma, Tai Young Kim, Seungmin Lee, Ah Reum Kim, Min Young Kim, Min A Kim, Mingyu Lee, Jin Hee Han, Jae Joon Han, , Byung Yoon Choi

This study identifies TMEM43 mutations as a cause of autosomal dominant auditory neuropathy spectrum disorder by showing their interaction with Connexin-mediated channels in cochlear glia-like supporting cells.

Proceedings of the National Academy of Sciences · May 28, 2021Peer-reviewedGenetics