Author

K. A. Zielinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:structural biology· 3 Research Focus:protein folding & dynamics· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. Pollack· 3 shared V. Mariani· 2 shared A. Barty· 1 shared A. M. Katz· 1 shared A. Mancuso· 1 shared A. OurmazdiD· 1 shared A. Sadri· 1 shared A. Tolstikova· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiophysics

L. Pollack

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3 papers

Recent·Most cited

Defining the conformational states that enable transglutaminase 2 to promote cancer cell survival versus cell death

C. Aplin, K. A. Zielinski, S. Pabit, D. Ogunribido, W. P. Katt, L. Pollack, R. A. Cerione, S. K. Milano

This paper investigates the conformational states of TG2 and shows how an inhibitor stabilizes an open conformation that is cytotoxic to cancer cells.

bioRxiv · Feb 4, 2024 · PreprintBiophysics

RNA structures and dynamics with A resolution revealed by x-ray free electron lasers

K. A. Zielinski, S. Sui, S. A. Pabit, D. A. Rivera, T. Wang, Q. Hu, M. M. Kashipathy, S. Lisova, C. B. Schaffer, V. Mariani, M. S. Hunter, C. J. Kupitz, F. R. Moss, F. P. Poitevin, T. D. Grant, L. Pollack

This paper reveals RNA structures and dynamics at near-atomic resolution using x-ray free electron lasers, showing how RNA folds through intermediate states and forms triplexes.

bioRxiv · May 24, 2023Biophysics

Direct Observation of the Mechanism of Antibiotic Resistance by Mix-and-Inject at the European XFEL

S. Pandey, G. Calvey, A. M. Katz, T. N. Malla, F. Koua, J. Martin-Garcia, I. Poudyal, J.-H. Yang, M. Vakili, O. Yefanov, K. A. Zielinski, S. Bajt, S. Awel, K. Doerner, M. Frank, , M. Schmidt

The paper directly observes fast ligand binding in a biomedically relevant enzyme using MHz X-ray pulses at the European XFEL.

bioRxiv · Nov 24, 2020 · PreprintBiophysics