Author

T. D. Grant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:benchmarking· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Assay:electronic health records· 1

Frequent Co-Authors

P. Fromme· 2 shared R. Fromme· 2 shared A. Ansari· 1 shared A. Grieco· 1 shared A. L. Pey· 1 shared A. Manna· 1 shared A. P. Mancuso· 1 shared A. Ros· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

P. Fromme

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Author profile →

5 papers

Recent·Most cited

Minimized Sample Consumption for Time-Resolved Serial Crystallography Applied to the Redox Cycle of Human NQO1

D. Doppler, A. Grieco, D. Koh, A. Manna, A. Ansari, R. Alvarez, K. Karpos, H. Le, M. Sonker, G. Ketawala, S. Mahmud, I. Quereda Moraleda, A. L. Pey, R. Letrun, K. Doerner, , A. Ros

This paper demonstrates a method to reduce sample consumption in time-resolved serial crystallography by using segmented droplet generation and mix-and-inject approaches for studying NQO1's redox cycle.

bioRxiv · Apr 29, 2024Biochemistry

Fitting high-resolution electron density maps from atomic models to solution scattering data

S. R. Chamberlain, S. Moore, T. D. Grant

This paper presents a method to predict solution X-ray scattering profiles from atomic models using high-resolution electron density maps, improving accuracy and reducing computational time.

bioRxiv · Jun 2, 2023Biophysics

RNA structures and dynamics with A resolution revealed by x-ray free electron lasers

K. A. Zielinski, S. Sui, S. A. Pabit, D. A. Rivera, T. Wang, Q. Hu, M. M. Kashipathy, S. Lisova, C. B. Schaffer, V. Mariani, M. S. Hunter, C. J. Kupitz, F. R. Moss, F. P. Poitevin, T. D. Grant, L. Pollack

This paper reveals RNA structures and dynamics at near-atomic resolution using x-ray free electron lasers, showing how RNA folds through intermediate states and forms triplexes.

bioRxiv · May 24, 2023Biophysics

Structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis

P. Fromme, N. Nagaratnam, J. M. Martin-Garcia, J.-H. Yang, M. R. Goode, G. Ketalawa, F. M. Craciunescu, J. D. Zook, T. D. Grant, R. Fromme, D. T. Hansen

This study determines the structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis, revealing its dimeric, two-domain organization.

bioRxiv · Apr 8, 2022Biochemistry

Describing small angle scattering profiles by a limited set of intensities

T. D. Grant

The paper extends an indirect Fourier transform algorithm for small angle scattering data by introducing new equations and a regularizer to improve accuracy and reduce systematic deviations.

bioRxiv · May 24, 2021Biophysics