ZBP1 induces inflammatory signaling via RIPK3 and promotes SARS-CoV-2-induced cytokine expression
R. Peng, X. Wang-Kan, M. Idorn, F. Y. Zhou, S. L. Orozco, J. McCarthy, C. S. Leung, X. Lu, K. Bagola, J. Rehwinkel, A. Oberst, J. Maelfait, S. R. Paludan, M. Gyrd-Hansen
This study identifies a ZBP1-RIPK1-RIPK3 pathway that promotes SARS-CoV-2-induced cytokine expression through inflammatory signaling independent of cell death.
bioRxiv · Oct 1, 2021 · PreprintImmunology