Author

K. Chaiyakul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

D. Lamming· 2 shared I. M. Ong· 2 shared R. Babygirija· 2 shared A. Bleicher· 1 shared A. Mehendale· 1 shared C. Green· 1 shared C. L. Green· 1 shared C.-Y. Yeh· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

D. Lamming

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2 papers

Recent·Most cited

Individual dietary amino acid restrictions induce distinct metabolic and chromatin states

S. Haws, Y. Liu, C. Green, K. Chaiyakul, P. Mishra, R. Babygirija, E. Armstrong, A. Mehendale, I. M. Ong, D. Lamming, J. M. Denu

The paper investigates how dietary restriction of specific essential amino acids affects metabolism and chromatin states in mice, finding distinct effects for methionine, leucine, and isoleucine.

bioRxiv · Dec 6, 2023 · PreprintBiochemistry

Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice

C. L. Green, M. E. Trautman, R. Babygirija, R. Jain, K. Chaiyakul, H. H. Pak, A. Bleicher, G. Novak, M. M. Sonsalla, C.-Y. Yeh, M. F. Calubag, T. T. Liu, V. Flores, S. Newman, W. A. Ricke, , D. Lamming

This study shows that reducing dietary isoleucine improves metabolic health, reduces frailty, and extends lifespan in genetically diverse mice.

bioRxiv · Oct 6, 2022Physiology