Author
K. D. McCoy
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2017-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 5 mutual co-author links6 papers
Recent·Most cited
Genomic Changes During the Evolution of the Coxiella Genus Along the Parasitism-Mutualism Continuum.
D. Santos-Garcia, O. Morel, H. Henri, A. El Filali, M. Buysse, V. Noël, K. D. McCoy, Y. Gottlieb, L. Klasson, L. Zenner, O. Duron, F. Vavre
This study sequenced two new Coxiella-LE genomes and analyzed 43 Coxiellaceae genomes to explore genomic changes related to parasitism and mutualism in the Coxiella genus.
bioRxiv · Oct 26, 2022Microbiology
Small Intestinal Resident Eosinophils Maintain Gut Homeostasis Following Microbial Colonisation
K. Shah, A. Ignacio, J. Bernier-Latmani, Y. Koeller, G. Coakley, M. Moyat, R. Hamelin, F. Armand, N. C. Wong, H. Remay, C. A. Thomson, R. Bukhard, A. Dufour, T. V. Petrova, N. L. Harris, K. D. McCoy
This study identifies eosinophils as critical regulators of intestinal homeostasis, barrier integrity, and motility following microbial colonization.
bioRxiv · Jan 30, 2021 · PreprintImmunology
Contribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice
E. van Tilburg Bernardes, V. Kucharova Pettersen, M. W. Gutierrez, I. Laforest-Lapointe, N. G. Jendzjowsky, J.-B. Cavin, F. A. Vicentini, C. M. Keenan, H. R. Ramay, J. Samara, W. K. MacNaughton, R. J. Wilson, M. M. Kelly, K. D. McCoy, K. A. Sharkey, M.-C. Arrieta
This study shows that fungi shape bacterial microbiome ecology and immune development in mice, but bacteria drive major intestinal and inflammatory changes.
bioRxiv · Oct 25, 2019 · PreprintMicrobiology
Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells
A. Drobek, A. Moudra, D. Mueller, M. Huranova, V. Horkova, M. Pribikova, R. Ivanek, S. Oberle, D. Zehn, K. D. McCoy, P. Draber, O. Stepanek
The paper shows that virtual memory CD8 T cells arise from strongly self-reactive T cells and are regulated by CD8-Lck stoichiometry, but do not exhibit increased autoimmune potential.
bioRxiv · Oct 13, 2017Immunology
Antibodies set boundaries limiting microbial metabolite penetration and the resultant mammalian host response
Y. Uchimura, T. Fuhrer, H. Li, M. A. Lawson, M. Zimmermann, M. Gomez de Aguero, B. Yilmaz, F. Ronchi, M. Sorribas, S. Hapfelmeier, S. C. Ganal-Vonarburg, K. D. McCoy, U. Sauer, A. J. Macpherson
The paper develops a model to distinguish microbial and host metabolites using stable isotope tracing and shows that antibodies limit microbial metabolite penetration into host tissues.
bioRxiv · Sep 25, 2017Immunology