Author

K. M. Sapp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. M. Westermark· 2 shared E. C. Lien· 2 shared M. Vander Heiden· 2 shared Z. Li· 2 shared A. M. Darnell· 1 shared A. N. Lau· 1 shared C. R. Chin· 1 shared D. A. Tuveson· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. M. Westermark

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Author profile →

2 papers

Recent·Most cited

Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma

A. N. Lau, Z. Li, L. V. Danai, A. M. Westermark, A. M. Darnell, R. Ferreira, V. Gocheva, S. Sivanand, E. C. Lien, K. M. Sapp, J. R. Mayers, G. Biffi, C. R. Chin, S. M. Davidson, D. A. Tuveson, , M. Vander Heiden

The paper uses isotope tracing to compare metabolism between cancer cells and fibroblasts in pancreatic tumors, identifying key metabolic dependencies in cancer cells.

bioRxiv · Mar 9, 2020Cancer Biology

Caloric restriction alters lipid metabolism to contribute to tumor growth inhibition

E. C. Lien, A. M. Westermark, Z. Li, K. M. Sapp, M. Vander Heiden

This study shows caloric restriction inhibits tumor growth by reducing lipid availability and impairing stearoyl-CoA desaturase activity in cancer cells.

bioRxiv · Mar 9, 2020 · PreprintCancer Biology