Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
M. P. Gold, W. Ong, A. M. Masteller, J. A. Galindo, N. R. Park, R. A. Saurez, M. C. Vladoiu, L. K. Donovan, A. D. Walker, J. Benetatos, L. Garzia, R. J. Wechsler-Reya, J. P. Mesirov, A. Korshunov, S. L. Pomeroy, , E. Fraenkel
The paper investigates SHH medulloblastoma heterogeneity by analyzing single-nucleus RNA-seq data and linking findings to developmental origins and molecular subtypes.
bioRxiv · Sep 2, 2022Cancer Biology
H. R. Foster, T. Ho, E. Potapenko, S. M. Sdao, S. L. Lewandowski, H. R. VanDeusen, S. M. Davidson, R. L. Cardone, M. Prentki, R. G. Kibbey, M. J. Merrins
This study identifies PKm1 and PKm2 as nutrient sensors that regulate β-cell KATP channels through mitochondrial PEP, influencing insulin secretion and Ca2+ oscillations.
bioRxiv · Feb 9, 2022 · PreprintCell Biology
K. Chellappa, M. R. McReynolds, W. Lu, X. Zeng, M. Makarov, F. Hayat, S. Mukherjee, Y. R. Bhat, S. R. Lingala, R. T. Shima, H. C. Descamps, T. Cox, L. Ji, C. Jankowski, Q. Chu, , J. A. Baur
The paper shows NAD precursors cycle between host tissues and the gut microbiome to maintain NAD homeostasis.
bioRxiv · Nov 15, 2021Physiology
M. V. Basalay, S. Arjun, S. M. Davidson, D. M. Yellon
This study investigates how the SGLT2 inhibitor ertugliflozin limits myocardial infarct size and finds that this effect is mediated through parasympathetic activation and M3-cholinoreceptor signaling.
bioRxiv · Oct 1, 2021 · PreprintPhysiology
S. M. Davidson, J. E. Heyman, J. P. O'Brien, A. C. Liu, D. R. Schmidt, W. J. Israelsen, T. L. Dayton, R. Sehgal, R. Bronson, E. Freinkman, H. Mak, S. Malstrom, G. Bellinger, A. Carracedo, P. P. Pandolfi, , M. G. Vander Heiden
The paper investigates the role of pyruvate kinase isoforms in prostate cancer, finding that Pkm1 suppresses cancer while Pkm2 promotes it, and that a PKM1-like activator can suppress tumor progression.
bioRxiv · May 9, 2021Cancer Biology
B. M. Jones, B. E. Rubin, O. Dudchenko, C. J. Kingwell, I. M. Traniello, Z. Y. Wang, K. M. Kapheim, E. S. Wyman, P. A. Adastra, W. Liu, L. R. Parsons, S. R. Jackson, K. Goodwin, S. M. Davidson, M. J. McBride, , S. D. Kocher
The paper identifies genomic signatures and loci associated with convergent gains and losses of eusociality in sweat bees, linking them to juvenile hormone signaling proteins.
bioRxiv · Apr 14, 2021Evolutionary Biology
A. N. Lau, Z. Li, L. V. Danai, A. M. Westermark, A. M. Darnell, R. Ferreira, V. Gocheva, S. Sivanand, E. C. Lien, K. M. Sapp, J. R. Mayers, G. Biffi, C. R. Chin, S. M. Davidson, D. A. Tuveson, , M. Vander Heiden
The paper uses isotope tracing to compare metabolism between cancer cells and fibroblasts in pancreatic tumors, identifying key metabolic dependencies in cancer cells.
bioRxiv · Mar 9, 2020Cancer Biology
B. Ngo, E. Kim, V. Osorio-Vasquez, S. Doll, S. Bustraan, A. Luengo, S. M. Davidson, A. Ali, G. D. Ferraro, D. Kang, J. Ni, R. Liang, A. Plasger, E. R. Kastenhuber, R. Eskandari, , M. E. Pacold
This study shows that brain metastases rely on PHGDH-mediated serine synthesis due to limited environmental serine, making them sensitive to PHGDH inhibition.
bioRxiv · Mar 3, 2020 · PreprintCancer Biology