K. P. Battaile

Molecular basis for the activation of the Fatty Acid Kinase complex of Staphylococcus aureus

This study investigates the structure and function of the Fatty Acid Kinase complex in Staphylococcus aureus using modeling, biochemical, and cell-based approaches, revealing key residues and interactions essential for its activity.

HSV-1 ICP0 Dimer Domain Adopts a Novel β-barrel Fold

This study determines the structure of the HSV-1 ICP0 dimer domain, revealing a novel β-barrel fold and its interactions with SUMO1.

Structure of a dominant negative mutant reveals a stalled intermediate in anthrax protective antigen pore maturation

The paper identifies a dominant negative mutation that stalls anthrax protective antigen pore maturation at an intermediate state, revealing structural features and a regulatory mechanism for pore formation.

The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform

The paper reports the structures of SctK and SctD from Pseudomonas aeruginosa, revealing their interaction interface in the T3SS and supporting a model for their functional relationship.

The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase

This paper identifies SARS-CoV-2's Mac1 as a mono-ADP-ribosylhydrolase, showing it binds and hydrolyzes mono-ADP-ribose, with implications for antiviral therapy.