Author

K. Qian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:protein structure· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. Lei· 2 shared S. Hu· 2 shared T. Li· 2 shared W. Fu· 2 shared A. Ma· 1 shared C. Ji· 1 shared C. Luo· 1 shared D. Cui· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

C. Lei

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Simulation study of Cell Transmembrane Potential and Electroporation Induced by Time-Varying Magnetic Fields

F. Guo, K. Qian, X. Li, D. Hao

This study simulates transmembrane potential and electroporation caused by time-varying magnetic fields, showing that nanosecond pulses are more effective than sub-microsecond pulses for membrane electroporation.

bioRxiv · Jul 21, 2022Biophysics

Emergence of an adaptive epigenetic cell state in human bladder urothelial carcinoma evolution

Y. Xiao, W. Jin, K. Qian, K. Wu, G. Wang, W. Jiang, R. Cao, L. Ju, Y. Zhao, H. Zheng, T. Liu, L. Chang, Z. Xu, T. Wang, J. Luo, , X. Wang

This study identifies a TM4SF1-positive cancer subpopulation in bladder cancer that drives intratumor heterogeneity and is associated with poor prognosis.

bioRxiv · Oct 30, 2021 · PreprintCancer Biology

CAR Macrophages for SARS-CoV-2 Immunotherapy

W. Fu, C. Lei, K. Qian, Z. Ma, T. Li, W. Zhang, F. Lin, J. Zhao, S. Hu

This study genetically modifies human macrophages with CARs to target SARS-CoV-2, showing that CARMERTK macrophages reduce viral load without increasing proinflammatory cytokines.

bioRxiv · Jul 26, 2020Bioengineering

Potent neutralization of 2019 novel coronavirus by recombinant ACE2-Ig

C. Lei, W. Fu, K. Qian, T. Li, S. Zhang, M. Ding, S. Hu

This study develops a recombinant ACE2-Ig fusion protein that neutralizes both SARS-CoV and 2019-nCoV in vitro, showing cross-reactivity and potential for diagnostic, prophylactic, and therapeutic applications.

bioRxiv · Feb 1, 2020 · PreprintBioengineering

The Dynamic Conformational Landscapes of the Protein Methyltransferase SETD8

S. Chen, R. P. Wiewiora, F. Meng, N. Babault, A. Ma, W. Yu, K. Qian, H. Hu, H. Zou, J. Wang, S. Fan, G. Blum, F. Pittella-Silva, K. A. Beauchamp, W. Tempel, , M. Luo

This study reveals dynamic conformational landscapes of SETD8 using X-ray structures and molecular simulations, showing how protein dynamics influence catalysis and cancer-associated mutations.

bioRxiv · Oct 12, 2018Biophysics